#0003

Diabetic ketoacidosis after missed insulin

Patient

19y · Female

Date

16 Sept 2026

DKAType 1 diabetesICU

Chief Complaint

Vomiting and stomach pain, very thirsty for 2 days

Clinical Case

age

19 years

sex

F

occupation

University student

Vomiting and stomach pain, very thirsty

Duration

2 days

History of Present Illness

onset

Gradual

associated symptoms

  • Polyuria
  • Polydipsia
  • Abdominal pain
  • Drowsiness

Current Medications

  • Insulin glargine 20 units nightly (missed 3 days)
  • Insulin aspart with meals

medical

Type 1 diabetes since age 11; one prior DKA admission

vitals

BP

95/60

HR

118

RR

28

TEMP

37.2

SPO2

99%

general

Kussmaul breathing, dry mucous membranes, ketotic breath

weight

52 kg

labs

  • Glucose 486 mg/dLOn arrival
  • VBG: pH 7.08, HCO₃ 8 mmol/LOn arrival
  • Serum ketones 5.8 mmol/LOn arrival
  • pH 7.31, HCO₃ 17 mmol/L12 hours

primary diagnosis

Severe diabetic ketoacidosis

differentials

  • Acute pancreatitis
  • Sepsis

medications

  • Normal saline1 L over 1 hour, then per protocolHour 0
  • Fixed-rate IV insulin0.1 units/kg/hourHour 1
  • Potassium chloride40 mmol/L in fluidsHour 2

referrals

  • Diabetes specialist nurse

follow up

Endocrine clinic in 4 weeks; sick-day rules education